Perio-Analyse® : biological analysis accessible to practitioners

The colonization of the mouth by periodontal bacteria can take place at an early age of the patient but can also take place after dental implant placement (peri-implantitis) if the patient was not being properly treated against pathogenic bacteria or having poor oral hygiene without dental maintenance.

A microbiological infection !

The origin of periodontal disease is the formation of bacterial biofilm with specific pathogenic bacteria and fungus . Certain pathogens at a certain level will increase the risk of periodontal disease or peri-implantitis. Bone lost could be more than 3 mm in 2 months with only 105 of aggressive bacteria into the pocket. Certain aggressive, anaerobic pathogenic bacteria are inside the soft tissue (intracellular) and require surgical procedure to eliminate contaminated soft and hard tissue.

The objectives of Perio-Analyse®

Choice of a suitable antibiotic and treatment evaluation in relation with bacterial strain identity and quantity.
Follow-up of treatment and support to maintenance protocol.
Early detection of the secondary infection or peri-implantitis (infectious disease after dental implant installation).
Motivation of patient to maintain their treatment and their oral hygiene in the long run

Real Time PCR

Microbial DNA extraction from paper points or saliva. DNA amplification with DNA probes and primers.
Multiparametric quantification of DNA bacterial specific sequences from gingival crevicular fluid , peri-implant sulcular fluid or saliva. Resistant bacterial strain identification.

Pathogenic bacteria strains and fungus associated with risk of periodontal disease or peri-implantitis

Pathogenic bacteria strains and fungus associated with risk of periodontal disease or peri-implantitis

  • Aggregatibacter actinomycetemcomitans
  • Porphyromonas gingivalis
  • Tannerella forsythensis
  • Treponema denticola
  • Prevotella intermedia
  • Peptostreptococcus micros
  • Fusobacterium nucleatum
  • Campylobacter rectus
  • Eikenella corrodens
  • Candida albicans

Situations to carry out Perio-Analyse®

  • first visit of patient with periodontal disease with depth of the pockets >4mm (in spite of a very good oral hygiene)
  • patients with gingivitis and smoker
  • diabetic patients
  • refractory periodontal disease resistant to the mechanical therapy
  • periodontal disease evolving/moving quickly
  • peri-implantitis risk patient
  • 3 months after periodontal treatment starting date
  • every year for all patients under maintenance